Cargando…

Perampanel in the management of partial-onset seizures: a review of safety, efficacy, and patient acceptability

Perampanel (PER) is a novel antiepileptic drug recently introduced for the adjunctive treatment in epilepsy patients aged 12 years or older with partial-onset seizures with or without secondary generalization in the US and Europe. Its antiepileptic action is based on noncompetitive inhibition of pos...

Descripción completa

Detalles Bibliográficos
Autores principales:	Schulze-Bonhage, Andreas, Hintz, Mandy
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2015
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4542413/ https://www.ncbi.nlm.nih.gov/pubmed/26316718 http://dx.doi.org/10.2147/PPA.S63951

Ejemplares similares

Clinical efficacy of perampanel for partial-onset and primary generalized tonic–clonic seizures
por: Besag, Frank MC, et al.
Publicado: (2016)

Profile of perampanel and its potential in the treatment of partial onset seizures
por: Rheims, Sylvain, et al.
Publicado: (2013)

Systematic Review and Meta-Analysis of the Efficacy and Safety of Perampanel in the Treatment of Partial-Onset Epilepsy
por: Hsu, Warrington W. Q., et al.
Publicado: (2013)

Efficacy and Safety of Perampanel in Children with Drug-Resistant Focal-Onset Seizures: A Retrospective Review
por: Elmardenly, Ahmed, et al.
Publicado: (2023)

Perampanel: What is its Place in the Management of Partial Onset Epilepsy?
por: Ledingham, David R. M., et al.
Publicado: (2013)

Cognitive effects of adjunctive perampanel for partial‐onset seizures: A randomized trial
por: Meador, Kimford J., et al.
Publicado: (2016)

Erratum to: Systematic Review and Meta-Analysis of the Efficacy and Safety of Perampanel in the Treatment of Partial-Onset Epilepsy
por: Hsu, Warrington W. Q., et al.
Publicado: (2013)

Perampanel efficacy and safety by gender: Subanalysis of phase III randomized clinical studies in subjects with partial seizures
por: Vazquez, Blanca, et al.
Publicado: (2015)

Long-term safety of perampanel and seizure outcomes in refractory partial-onset seizures and secondarily generalized seizures: Results from phase III extension study 307
por: Krauss, Gregory L, et al.
Publicado: (2014)

An Evidence-Based Review On The Use Of Perampanel For The Treatment Of Focal-Onset Seizures In Pediatric Patients
por: Dozières-Puyravel, Blandine, et al.
Publicado: (2019)

The efficacy and safety of adjunctive perampanel for the treatment of refractory focal‐onset seizures in patients with epilepsy: A meta‐analysis
por: Li, Yiming, et al.
Publicado: (2022)

Impact of perampanel on pharmacokinetics of concomitant antiepileptics in patients with partial‐onset seizures: pooled analysis of clinical trials
por: Majid, Oneeb, et al.
Publicado: (2016)

Value of Perampanel as Adjunctive Treatment for Partial-Onset Seizures in Epilepsy: Cost-Effectiveness and Budget Impact Analysis
por: Zhang, Donger, et al.
Publicado: (2021)

New drug classes for the treatment of partial onset epilepsy: focus on perampanel
por: Shih, Jerry J, et al.
Publicado: (2013)

Spotlight on perampanel in the management of seizures: design, development and an update on place in therapy
por: Faulkner, Michele A
Publicado: (2017)

Efficacy and Tolerability of Perampanel as Adjunctive Therapy in Chinese Patients With Focal-Onset Seizures: An Observational, Prospective Study
por: Zhang, Ranran, et al.
Publicado: (2021)

First add‐on perampanel for focal‐onset seizures: An open‐label, prospective study
por: Kim, Ji Hyun, et al.
Publicado: (2019)

Efficacy and safety of perampanel monotherapy in Chinese patients with focal‐onset seizures: A single‐center, prospective, real‐world observational study
por: Ma, Haiyan, et al.
Publicado: (2023)

Efficacy and safety of perampanel as early add-on therapy in Chinese patients with focal-onset seizures: a multicenter, open-label, single-arm study
por: Gao, Lehong, et al.
Publicado: (2023)

Safety and efficacy of levetiracetam for the treatment of partial onset seizures in children from one month of age
por: Cormier, Justine, et al.
Publicado: (2013)

Efficacy of Retigabine in Adjunctive Treatment of Partial Onset Seizures in Adults
por: Splinter, Michele Y.
Publicado: (2013)

Spectral bandwidth of interictal fast epileptic activity characterizes the seizure onset zone
por: Heers, Marcel, et al.
Publicado: (2017)

Efficacy and safety of brivaracetam for partial-onset seizures in 3 pooled clinical studies
por: Ben-Menachem, Elinor, et al.
Publicado: (2016)

Perampanel-Induced, New-Onset Thrombocytopenia in a Patient With Refractory Seizures: A Case Report
por: Almuhanna, Rakan A, et al.
Publicado: (2023)

Perampanel as First Adjunctive Treatment in Patients with Focal-Onset Seizures in the FAME Study: Post hoc Analyses of Dose-Related Efficacy, Safety and Clinical Factors Associated with Response
por: Kim, Dong Wook, et al.
Publicado: (2022)

Buccal midazolam for pediatric convulsive seizures: efficacy, safety, and patient acceptability
por: Anderson, Mark
Publicado: (2013)

Seizure control and improvement of neurological dysfunction in Lafora disease with perampanel
por: Dirani, Maya, et al.
Publicado: (2014)

Seizure remission and improvement of neurological function in sialidosis with perampanel therapy
por: Hu, Su-Ching, et al.
Publicado: (2018)

Assessment of the long‐term efficacy and safety of adjunctive perampanel in tonic‐clonic seizures: Analysis of four open‐label extension studies
por: Rektor, Ivan, et al.
Publicado: (2020)

Efficacy and tolerability of perampanel in patients with seizures in real-world clinical practice: A systematic review and meta-analysis
por: Hou, Liyan, et al.
Publicado: (2023)

Perampanel as First Add-On Therapy in Patients with Focal-Onset Seizures in the FAME Trial: Post hoc Analyses of Efficacy and Safety Related to Maintenance Dose and Background Antiepileptic Drug Therapy
por: Kim, Ji Hyun, et al.
Publicado: (2022)

Exploring the Evidence for Broad-Spectrum Effectiveness of Perampanel: A Systematic Review of Clinical Data in Generalised Seizures
por: Trinka, Eugen, et al.
Publicado: (2021)

Termination of seizures by ictal transcranial focal cortex stimulation
por: Hirsch, Martin, et al.
Publicado: (2023)

Lacosamide for the prevention of partial onset seizures in epileptic adults
por: Kelemen, Anna, et al.
Publicado: (2010)

Open‐label study to investigate the safety and efficacy of adjunctive perampanel in pediatric patients (4 to <12 years) with inadequately controlled focal seizures or generalized tonic‐clonic seizures
por: Fogarasi, Andras, et al.
Publicado: (2020)

Efficacy and safety of perampanel monotherapy in patients with focal‐onset seizures with newly diagnosed epilepsy or recurrence of epilepsy after a period of remission: The open‐label Study 342 (FREEDOM Study)
por: Yamamoto, Takamichi, et al.
Publicado: (2020)

Food intake precipitates seizures in temporal lobe epilepsy
por: Tényi, Dalma, et al.
Publicado: (2021)

Sustained seizure remission on perampanel in progressive myoclonic epilepsy (Lafora disease)()
por: Schorlemmer, Kathrin, et al.
Publicado: (2013)

The Effectiveness of Perampanel for Myoclonic Seizures in Down Syndrome with Isodicentric Chromosome 21
por: Obara, Koji, et al.
Publicado: (2020)

Perampanel Reduces Hyperthermia-Induced Seizures in Dravet Syndrome Mouse Model
por: Ho, Shih-Yin, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_8k5a872hunbhqojo4g2er3142s