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Mechanism of Altered Metformin Distribution in Nonalcoholic Steatohepatitis

Metformin is an antihyperglycemic drug that is widely prescribed for type 2 diabetes mellitus and is currently being investigated for the treatment of nonalcoholic steatohepatitis (NASH). NASH is known to alter hepatic membrane transporter expression and drug disposition similarly in humans and rode...

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Detalles Bibliográficos
Autores principales:	Clarke, John D., Dzierlenga, Anika L., Nelson, Nicholas R., Li, Hui, Werts, Samantha, Goedken, Michael J., Cherrington, Nathan J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2015
Materias:	Complications
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4542448/ https://www.ncbi.nlm.nih.gov/pubmed/26016715 http://dx.doi.org/10.2337/db14-1947

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