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Retinal prostheses: progress toward the next generation implants
In the last decade, various clinical trials proved the capability of visual prostheses, in particular retinal implants, to restore a useful form of vision. These encouraging results promoted the emerging of several strategies for neuronal stimulation aiming at the restoration of sight. Besides the t...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4542462/ https://www.ncbi.nlm.nih.gov/pubmed/26347602 http://dx.doi.org/10.3389/fnins.2015.00290 |
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author | Ghezzi, Diego |
author_facet | Ghezzi, Diego |
author_sort | Ghezzi, Diego |
collection | PubMed |
description | In the last decade, various clinical trials proved the capability of visual prostheses, in particular retinal implants, to restore a useful form of vision. These encouraging results promoted the emerging of several strategies for neuronal stimulation aiming at the restoration of sight. Besides the traditional approach based on electrical stimulation through metal electrodes in the different areas of the visual path (e.g., the visual cortex, the lateral geniculate nucleus, the optic nerve, and the retina), novel concepts for neuronal stimulation have been mostly exploited as building blocks of the next generation of retinal implants. This review is focused on critically discussing recent major advancements in the field of retinal stimulation with particular attention to the findings in the application of novel concepts and materials. Last, the major challenges in the field and their clinical implications will be outlined. |
format | Online Article Text |
id | pubmed-4542462 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-45424622015-09-07 Retinal prostheses: progress toward the next generation implants Ghezzi, Diego Front Neurosci Neuroscience In the last decade, various clinical trials proved the capability of visual prostheses, in particular retinal implants, to restore a useful form of vision. These encouraging results promoted the emerging of several strategies for neuronal stimulation aiming at the restoration of sight. Besides the traditional approach based on electrical stimulation through metal electrodes in the different areas of the visual path (e.g., the visual cortex, the lateral geniculate nucleus, the optic nerve, and the retina), novel concepts for neuronal stimulation have been mostly exploited as building blocks of the next generation of retinal implants. This review is focused on critically discussing recent major advancements in the field of retinal stimulation with particular attention to the findings in the application of novel concepts and materials. Last, the major challenges in the field and their clinical implications will be outlined. Frontiers Media S.A. 2015-08-20 /pmc/articles/PMC4542462/ /pubmed/26347602 http://dx.doi.org/10.3389/fnins.2015.00290 Text en Copyright © 2015 Ghezzi. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Neuroscience Ghezzi, Diego Retinal prostheses: progress toward the next generation implants |
title | Retinal prostheses: progress toward the next generation implants |
title_full | Retinal prostheses: progress toward the next generation implants |
title_fullStr | Retinal prostheses: progress toward the next generation implants |
title_full_unstemmed | Retinal prostheses: progress toward the next generation implants |
title_short | Retinal prostheses: progress toward the next generation implants |
title_sort | retinal prostheses: progress toward the next generation implants |
topic | Neuroscience |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4542462/ https://www.ncbi.nlm.nih.gov/pubmed/26347602 http://dx.doi.org/10.3389/fnins.2015.00290 |
work_keys_str_mv | AT ghezzidiego retinalprosthesesprogresstowardthenextgenerationimplants |