RNA-seq reveals the critical role of OtpR in regulating Brucella melitensis metabolism and virulence under acidic stress

The response regulator OtpR is critical for the growth, morphology and virulence of Brucella melitensis. Compared to its wild type strain 16 M, B. melitensis 16 MΔotpR mutant has decreased tolerance to acid stress. To analyze the genes regulated by OtpR under acid stress, we performed RNA-seq whole...

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Detalles Bibliográficos
Autores principales: Liu, Wenxiao, Dong, Hao, Li, Jing, Ou, Qixing, Lv, Yujin, Wang, Xiaolei, Xiang, Zuoshuang, He, Yongqun, Wu, Qingmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4542472/
https://www.ncbi.nlm.nih.gov/pubmed/26242322
http://dx.doi.org/10.1038/srep10864

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