Quantitative and qualitative characterization of expanded CD4(+) T cell clones in rheumatoid arthritis patients

Rheumatoid arthritis (RA) is an autoimmune destructive arthritis associated with CD4(+) T cell-mediated immunity. Although expanded CD4(+) T cell clones (ECs) has already been confirmed, the detailed characteristics of ECs have not been elucidated in RA. Using combination of a single-cell analysis a...

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Detalles Bibliográficos
Autores principales: Ishigaki, Kazuyoshi, Shoda, Hirofumi, Kochi, Yuta, Yasui, Tetsuro, Kadono, Yuho, Tanaka, Sakae, Fujio, Keishi, Yamamoto, Kazuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4542667/
https://www.ncbi.nlm.nih.gov/pubmed/26245356
http://dx.doi.org/10.1038/srep12937

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