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Identification of causal genes for complex traits

Motivation: Although genome-wide association studies (GWAS) have identified thousands of variants associated with common diseases and complex traits, only a handful of these variants are validated to be causal. We consider ‘causal variants’ as variants which are responsible for the association signa...

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Detalles Bibliográficos
Autores principales: Hormozdiari, Farhad, Kichaev, Gleb, Yang, Wen-Yun, Pasaniuc, Bogdan, Eskin, Eleazar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4542778/
https://www.ncbi.nlm.nih.gov/pubmed/26072484
http://dx.doi.org/10.1093/bioinformatics/btv240