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The potential of the riboSNitch in personalized medicine

RNA conformation plays a significant role in stability, ligand binding, transcription, and translation. Single nucleotide variants (SNVs) have the potential to disrupt specific structural elements because RNA folds in a sequence‐specific manner. A riboSNitch is an element of RNA structure with a spe...

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Detalles Bibliográficos
Autores principales: Solem, Amanda C., Halvorsen, Matthew, Ramos, Silvia B. V., Laederach, Alain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4543445/
https://www.ncbi.nlm.nih.gov/pubmed/26115028
http://dx.doi.org/10.1002/wrna.1291