Cargando…
The potential of the riboSNitch in personalized medicine
RNA conformation plays a significant role in stability, ligand binding, transcription, and translation. Single nucleotide variants (SNVs) have the potential to disrupt specific structural elements because RNA folds in a sequence‐specific manner. A riboSNitch is an element of RNA structure with a spe...
Autores principales: | Solem, Amanda C., Halvorsen, Matthew, Ramos, Silvia B. V., Laederach, Alain |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4543445/ https://www.ncbi.nlm.nih.gov/pubmed/26115028 http://dx.doi.org/10.1002/wrna.1291 |
Ejemplares similares
-
Detecting riboSNitches with RNA folding algorithms: a genome-wide benchmark
por: Corley, Meredith, et al.
Publicado: (2015) -
Experimental demonstration and pan-structurome prediction of climate-associated riboSNitches in Arabidopsis
por: Ferrero-Serrano, Ángel, et al.
Publicado: (2022) -
Identification and analysis of RNA structural disruptions induced by single nucleotide variants using Riprap and RiboSNitchDB
por: Lin, Jianan, et al.
Publicado: (2020) -
Transcending the prediction paradigm: novel applications of SHAPE to RNA function and evolution
por: Kutchko, Katrina M., et al.
Publicado: (2016) -
A unified analytic framework for prioritization of non-coding variants of uncertain significance in heritable breast and ovarian cancer
por: Mucaki, Eliseos J., et al.
Publicado: (2016)