Alpha7 nicotinic acetylcholine receptor is required for blood-brain barrier injury-related CNS disorders caused by Cryptococcus neoformans and HIV-1 associated comorbidity factors

BACKGROUND: Cryptococcal meningitis is the most common fungal infection of the central nervous system (CNS) in HIV/AIDS. HIV-1 virotoxins (e.g., gp41) are able to induce disorders of the blood-brain barrier (BBB), which mainly consists of BMEC. Our recent study suggests that α7 nAChR is an essential...

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Detalles Bibliográficos
Autores principales: Zhang, Bao, Yu, Jing-Yi, Liu, Li-Qun, Peng, Liang, Chi, Feng, Wu, Chun-Hua, Jong, Ambrose, Wang, Shi-Fu, Cao, Hong, Huang, Sheng-He
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4543465/
https://www.ncbi.nlm.nih.gov/pubmed/26285576
http://dx.doi.org/10.1186/s12879-015-1075-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4543465/
https://www.ncbi.nlm.nih.gov/pubmed/26285576
http://dx.doi.org/10.1186/s12879-015-1075-9

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