A convex formulation for joint RNA isoform detection and quantification from multiple RNA-seq samples

BACKGROUND: Detecting and quantifying isoforms from RNA-seq data is an important but challenging task. The problem is often ill-posed, particularly at low coverage. One promising direction is to exploit several samples simultaneously. RESULTS: We propose a new method for solving the isoform deconvol...

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Detalles Bibliográficos
Autores principales: Bernard, Elsa, Jacob, Laurent, Mairal, Julien, Viara, Eric, Vert, Jean-Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4543468/
https://www.ncbi.nlm.nih.gov/pubmed/26286719
http://dx.doi.org/10.1186/s12859-015-0695-9

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