Therapeutic Hypothermia and Hypoxia-Ischemia in the Term-equivalent Neonatal Rat: Characterization of a Translational Pre-clinical Model

BACKGROUND: Hypoxic-ischemic encephalopathy (HIE) is a major cause of morbidity in survivors. Therapeutic hypothermia (TH) is the only available intervention, but the protection is incomplete. Preclinical studies of HIE/TH in the rodent have relied on the postnatal day (P) 7 rat whose brain approxim...

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Detalles Bibliográficos
Autores principales: Patel, Shyama D., Pierce, Leslie, Ciardiello, Amber, Hutton, Alexandra, Paskewitz, Samuel, Aronowitz, Eric, Voss, Henning U., Moore, Holly, Vannucci, Susan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4543535/
https://www.ncbi.nlm.nih.gov/pubmed/25996893
http://dx.doi.org/10.1038/pr.2015.100

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