Inactivated Enterovirus 71 Vaccine Produced by 200-L Scale Serum-Free Microcarrier Bioreactor System Provides Cross-Protective Efficacy in Human SCARB2 Transgenic Mouse

Epidemics and outbreaks caused by infections of several subgenotypes of EV71 and other serotypes of coxsackie A viruses have raised serious public health concerns in the Asia-Pacific region. These concerns highlight the urgent need to develop a scalable manufacturing platform for producing an effect...

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Detalles Bibliográficos
Autores principales: Wu, Chia-Ying, Lin, Yi-Wen, Kuo, Chia-Ho, Liu, Wan-Hsin, Tai, Hsiu-Fen, Pan, Chien-Hung, Chen, Yung-Tsung, Hsiao, Pei-Wen, Chan, Chi-Hsien, Chang, Ching-Chuan, Liu, Chung-Cheng, Chow, Yen-Hung, Chen, Juine-Ruey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4543551/
https://www.ncbi.nlm.nih.gov/pubmed/26287531
http://dx.doi.org/10.1371/journal.pone.0136420

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