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Protein Hydroxylation Catalyzed by 2-Oxoglutarate-dependent Oxygenases

The post-translational hydroxylation of prolyl and lysyl residues, as catalyzed by 2-oxoglutarate (2OG)-dependent oxygenases, was first identified in collagen biosynthesis. 2OG oxygenases also catalyze prolyl and asparaginyl hydroxylation of the hypoxia-inducible factors that play important roles in...

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Detalles Bibliográficos
Autores principales:	Markolovic, Suzana, Wilkins, Sarah E., Schofield, Christopher J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2015
Materias:	Minireviews
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4543633/ https://www.ncbi.nlm.nih.gov/pubmed/26152730 http://dx.doi.org/10.1074/jbc.R115.662627

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