Current theoretical models fail to predict the topological complexity of the human genome

Understanding the folding of the human genome is a key challenge of modern structural biology. The emergence of chromatin conformation capture assays (e.g., Hi-C) has revolutionized chromosome biology and provided new insights into the three dimensional structure of the genome. The experimental data...

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Detalles Bibliográficos
Autores principales: Arsuaga, Javier, Jayasinghe, Reyka G., Scharein, Robert G., Segal, Mark R., Stolz, Robert H., Vazquez, Mariel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4543886/
https://www.ncbi.nlm.nih.gov/pubmed/26347874
http://dx.doi.org/10.3389/fmolb.2015.00048

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4543886/
https://www.ncbi.nlm.nih.gov/pubmed/26347874
http://dx.doi.org/10.3389/fmolb.2015.00048

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