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Diversity and Inter-Connections in the CXCR4 Chemokine Receptor/Ligand Family: Molecular Perspectives

CXCR4 and its ligand CXCL12 mediate the homing of progenitor cells in the bone marrow and their recruitment to sites of injury, as well as affect processes such as cell arrest, survival, and angiogenesis. CXCL12 was long thought to be the sole CXCR4 ligand, but more recently the atypical chemokine m...

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Detalles Bibliográficos
Autores principales: Pawig, Lukas, Klasen, Christina, Weber, Christian, Bernhagen, Jürgen, Noels, Heidi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4543903/
https://www.ncbi.nlm.nih.gov/pubmed/26347749
http://dx.doi.org/10.3389/fimmu.2015.00429

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