Rheostatic Regulation of the SERCA/Phospholamban Membrane Protein Complex Using Non-Coding RNA and Single-Stranded DNA oligonucleotides

The membrane protein complex between sarco(endo)plasmic reticulum Ca(2+)-ATPase (SERCA) and phospholamban (PLN) is a prime therapeutic target for reversing cardiac contractile dysfunctions caused by calcium mishandling. So far, however, efforts to develop drugs specific for this protein complex have...

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Detalles Bibliográficos
Autores principales: Soller, Kailey J., Verardi, Raffaello, Jing, Meng, Abrol, Neha, Yang, Jing, Walsh, Naomi, Vostrikov, Vitaly V., Robia, Seth L., Bowser, Michael T., Veglia, Gianluigi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4543939/
https://www.ncbi.nlm.nih.gov/pubmed/26292938
http://dx.doi.org/10.1038/srep13000

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