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Expression of hepatic Fibroblast Growth Factor 19 is enhanced in Primary Biliary Cirrhosis and correlates with severity of the disease

Cholestasis induces adaptive mechanisms protecting the liver against bile acids (BA) toxicity including modulation of BA synthesis. Whether fibroblast growth factor 19 (FGF19) or farnesoid X receptor (FXR) dependent signaling are involved in the regulation of BA homeostasis in primary biliary cirrho...

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Detalles Bibliográficos
Autores principales:	Wunsch, Ewa, Milkiewicz, Małgorzata, Wasik, Urszula, Trottier, Jocelyn, Kempińska-Podhorodecka, Agnieszka, Elias, Elwyn, Barbier, Olivier, Milkiewicz, Piotr
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4544021/ https://www.ncbi.nlm.nih.gov/pubmed/26293907 http://dx.doi.org/10.1038/srep13462

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