Integrated Simulation Framework for Toxicity, Dose Intensity, Disease Progression, and Cost Effectiveness for Castration-Resistant Prostate Cancer Treatment With Eribulin

Quantitative model-based analyses are helpful to support decision-making in drug development. In oncology, disease progression/clinical outcome (DPCO) models have been used for early predictions of clinical outcome, but most of such approaches did not include adverse events or dose intensity. In add...

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Detalles Bibliográficos
Autores principales: van Hasselt, JGC, Gupta, A, Hussein, Z, Beijnen, JH, Schellens, JHM, Huitema, ADR
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4544051/
https://www.ncbi.nlm.nih.gov/pubmed/26312161
http://dx.doi.org/10.1002/psp4.48

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