Relationships Between Pharmacovigilance, Molecular, Structural, and Pathway Data: Revealing Mechanisms for Immune-Mediated Drug-Induced Liver Injury

Immune-mediated drug-induced liver injury (IMDILI) can be devastating, irreversible, and fatal in the absence of successful transplantation surgery. We present a novel approach that combines the methods of pharmacoepidemiology with in silico molecular modeling to identify specific features in toxic...

Descripción completa

Detalles Bibliográficos
Autores principales: Ho, SS, McLachlan, AJ, Chen, TF, Hibbs, DE, Fois, RA
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4544056/
https://www.ncbi.nlm.nih.gov/pubmed/26312166
http://dx.doi.org/10.1002/psp4.56

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4544056/
https://www.ncbi.nlm.nih.gov/pubmed/26312166
http://dx.doi.org/10.1002/psp4.56

Ejemplares similares