Cargando…
Cadherin signaling: keeping cells in touch
Cadherin-catenin complexes are critical for the assembly of cell-cell adhesion structures known as adherens junctions. In addition to the mechanical linkage of neighboring cells to each other, these cell-cell adhesion protein complexes have recently emerged as important sensors and transmitters of t...
Autores principales: | , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
F1000Research
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4544379/ https://www.ncbi.nlm.nih.gov/pubmed/26339481 http://dx.doi.org/10.12688/f1000research.6445.1 |
_version_ | 1782386663895334912 |
---|---|
author | Klezovitch, Olga Vasioukhin, Valeri |
author_facet | Klezovitch, Olga Vasioukhin, Valeri |
author_sort | Klezovitch, Olga |
collection | PubMed |
description | Cadherin-catenin complexes are critical for the assembly of cell-cell adhesion structures known as adherens junctions. In addition to the mechanical linkage of neighboring cells to each other, these cell-cell adhesion protein complexes have recently emerged as important sensors and transmitters of the extracellular cues inside the cell body and into the nucleus. In the past few years, multiple studies have identified a connection between the cadherin-catenin protein complexes and major intracellular signaling pathways. Those studies are the main focus of this review. |
format | Online Article Text |
id | pubmed-4544379 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | F1000Research |
record_format | MEDLINE/PubMed |
spelling | pubmed-45443792015-09-02 Cadherin signaling: keeping cells in touch Klezovitch, Olga Vasioukhin, Valeri F1000Res Review Cadherin-catenin complexes are critical for the assembly of cell-cell adhesion structures known as adherens junctions. In addition to the mechanical linkage of neighboring cells to each other, these cell-cell adhesion protein complexes have recently emerged as important sensors and transmitters of the extracellular cues inside the cell body and into the nucleus. In the past few years, multiple studies have identified a connection between the cadherin-catenin protein complexes and major intracellular signaling pathways. Those studies are the main focus of this review. F1000Research 2015-08-12 /pmc/articles/PMC4544379/ /pubmed/26339481 http://dx.doi.org/10.12688/f1000research.6445.1 Text en Copyright: © 2015 Klezovitch O and Vasioukhin V http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Klezovitch, Olga Vasioukhin, Valeri Cadherin signaling: keeping cells in touch |
title | Cadherin signaling: keeping cells in touch |
title_full | Cadherin signaling: keeping cells in touch |
title_fullStr | Cadherin signaling: keeping cells in touch |
title_full_unstemmed | Cadherin signaling: keeping cells in touch |
title_short | Cadherin signaling: keeping cells in touch |
title_sort | cadherin signaling: keeping cells in touch |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4544379/ https://www.ncbi.nlm.nih.gov/pubmed/26339481 http://dx.doi.org/10.12688/f1000research.6445.1 |
work_keys_str_mv | AT klezovitcholga cadherinsignalingkeepingcellsintouch AT vasioukhinvaleri cadherinsignalingkeepingcellsintouch |