An Open-Label Investigation into Drug–Drug Interactions Between Multiple Doses of Daclatasvir and Single-Dose Cyclosporine or Tacrolimus in Healthy Subjects

BACKGROUND AND OBJECTIVE: Chronic hepatitis C virus (HCV) infection is a major cause of liver transplantation. Drug–drug interactions (DDIs) with cyclosporine and tacrolimus hindered the use of first-generation protease inhibitors in transplant recipients. The current study investigated DDIs between...

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Detalles Bibliográficos
Autores principales: Bifano, Marc, Adamczyk, Robert, Hwang, Carey, Kandoussi, Hamza, Marion, Alan, Bertz, Richard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2015
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4544506/
https://www.ncbi.nlm.nih.gov/pubmed/25896946
http://dx.doi.org/10.1007/s40261-015-0279-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4544506/
https://www.ncbi.nlm.nih.gov/pubmed/25896946
http://dx.doi.org/10.1007/s40261-015-0279-5

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