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Lefty-1 alleviates TGF-β1-induced fibroblast–myofibroblast transdifferentiation in NRK-49F cells
Fibroblast activation and proliferation are important for fibroblast–myofibroblast transdifferentiation, a crucial process in the pathological changes that define renal interstitial fibrosis. The left–right determination factor (Lefty) is an important cytokine of the transforming growth factor (TGF)...
Autores principales: | Zhang, Lijun, Zhang, Jie, Xu, Changgeng, Zhou, Xiangjun, Wang, Wei, Zheng, Renping, Hu, Wei, Wu, Pin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4544629/ https://www.ncbi.nlm.nih.gov/pubmed/26316705 http://dx.doi.org/10.2147/DDDT.S86770 |
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