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Genetically modified "obligate" anaerobic Salmonella typhimurium as a therapeutic strategy for neuroblastoma
BACKGROUND: Neuroblastoma currently has poor prognosis, therefore we proposed a new strategy by targeting neuroblastoma with genetically engineered anaerobic Salmonella (Sal-YB1). METHODS: Nude and nonobese diabetic-severe combined immunodeficiency (NOD-SCID) orthotopic mouse models were used, and S...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4545364/ https://www.ncbi.nlm.nih.gov/pubmed/26286454 http://dx.doi.org/10.1186/s13045-015-0196-3 |