Cargando…
Amino acid consumption in naïve and recombinant CHO cell cultures: producers of a monoclonal antibody
Most commercial media for mammalian cell culture are designed to satisfy the amino acid requirements for cell growth, but not necessarily those for recombinant protein production. In this study, we analyze the amino acid consumption pattern in naïve and recombinant Chinese hamster ovary (CHO) cell c...
Autores principales: | Carrillo-Cocom, L. M., Genel-Rey, T., Araíz-Hernández, D., López-Pacheco, F., López-Meza, J., Rocha-Pizaña, M. R., Ramírez-Medrano, A., Alvarez, M. M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4545443/ https://www.ncbi.nlm.nih.gov/pubmed/24798809 http://dx.doi.org/10.1007/s10616-014-9720-5 |
Ejemplares similares
-
Using simple models to describe the kinetics of growth, glucose consumption, and monoclonal antibody formation in naive and infliximab producer CHO cells
por: López-Meza, Julián, et al.
Publicado: (2015) -
Reduction in C-terminal amidated species of recombinant monoclonal antibodies by genetic modification of CHO cells
por: Škulj, Mihaela, et al.
Publicado: (2014) -
Comprehensive characterization of glutamine synthetase-mediated selection for the establishment of recombinant CHO cells producing monoclonal antibodies
por: Noh, Soo Min, et al.
Publicado: (2018) -
Application of maltose as energy source in protein-free CHO-K1 culture to improve the production of recombinant monoclonal antibody
por: Leong, Dawn Sow Zong, et al.
Publicado: (2018) -
Evaluation of site-specific methylation of the CMV promoter and its role in CHO cell productivity of a recombinant monoclonal antibody
por: Dahodwala, Hussain, et al.
Publicado: (2022)