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An algorithm for the reduction of genome-scale metabolic network models to meaningful core models

BACKGROUND: Constraint-based analysis of genome-scale metabolic models has become a key methodology to gain insights into functions, capabilities, and properties of cellular metabolism. Since their inception, the size and complexity of genome-scale metabolic reconstructions has significantly increas...

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Detalles Bibliográficos
Autores principales: Erdrich, Philipp, Steuer, Ralf, Klamt, Steffen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4545695/
https://www.ncbi.nlm.nih.gov/pubmed/26286864
http://dx.doi.org/10.1186/s12918-015-0191-x