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6-Formylindolo(3,2-b)Carbazole (FICZ) Modulates the Signalsome Responsible for RA-Induced Differentiation of HL-60 Myeloblastic Leukemia Cells

6-Formylindolo(3,2-b)carbazole (FICZ) is a photoproduct of tryptophan and an endogenous high affinity ligand for aryl hydrocarbon receptor (AhR). It was previously reported that, in patient-derived HL-60 myeloblastic leukemia cells, retinoic acid (RA)-induced differentiation is driven by a signalsom...

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Detalles Bibliográficos
Autores principales:	Bunaciu, Rodica P., Jensen, Holly A., MacDonald, Robert J., LaTocha, Dorian H., Varner, Jeffrey D., Yen, Andrew
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4545789/ https://www.ncbi.nlm.nih.gov/pubmed/26287494 http://dx.doi.org/10.1371/journal.pone.0135668

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