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M1 and M2 macrophages derived from THP-1 cells differentially modulate the response of cancer cells to etoposide
BACKGROUND: Tumor associated macrophages (TAMs) are present in high density in solid tumors. TAMs share many characteristics with alternatively activated macrophages, also called M2. They have been shown to favor tumor development and a role in chemoresistance has also been suggested. Here, we inves...
Autores principales: | Genin, Marie, Clement, Francois, Fattaccioli, Antoine, Raes, Martine, Michiels, Carine |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4545815/ https://www.ncbi.nlm.nih.gov/pubmed/26253167 http://dx.doi.org/10.1186/s12885-015-1546-9 |
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