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Reliable scaling of position weight matrices for binding strength comparisons between transcription factors
BACKGROUND: Scoring DNA sequences against Position Weight Matrices (PWMs) is a widely adopted method to identify putative transcription factor binding sites. While common bioinformatics tools produce scores that can reflect the binding strength between a specific transcription factor and the DNA, th...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4545934/ https://www.ncbi.nlm.nih.gov/pubmed/26289072 http://dx.doi.org/10.1186/s12859-015-0666-1 |