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Neurogenin 3 Expressing Cells in the Human Exocrine Pancreas Have the Capacity for Endocrine Cell Fate
Neurogenin 3 (NGN3) is necessary and sufficient for endocrine differentiation during pancreatic development and is expressed by a population of progenitor cells that give rise exclusively to hormone-secreting cells within islets. NGN3 protein can be detected in the adult rodent pancreas only followi...
Autores principales: | Gomez, Danielle L., O’Driscoll, Marci, Sheets, Timothy P., Hruban, Ralph H., Oberholzer, Jose, McGarrigle, James J., Shamblott, Michael J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4545947/ https://www.ncbi.nlm.nih.gov/pubmed/26288179 http://dx.doi.org/10.1371/journal.pone.0133862 |
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