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TRIM28 as a novel transcriptional elongation factor

TRIM28 is a multidomain protein with versatile functions in transcription and DNA repair. Recently it was shown that this factor plays unanticipated roles in transcriptional elongation. TRIM28 was shown to stabilize the pausing of RNA polymerase II (Pol II) close to the transcriptional start site in...

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Detalles Bibliográficos
Autores principales: Bunch, Heeyoun, Calderwood, Stuart K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4545989/
https://www.ncbi.nlm.nih.gov/pubmed/26293668
http://dx.doi.org/10.1186/s12867-015-0040-x