Genetic Ablation of CD38 Protects against Western Diet-Induced Exercise Intolerance and Metabolic Inflexibility

Nicotinamide adenine dinucleotide (NAD(+)) is a key cofactor required for essential metabolic oxidation-reduction reactions. It also regulates various cellular activities, including gene expression, signaling, DNA repair and calcium homeostasis. Intracellular NAD(+) levels are tightly regulated and...

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Detalles Bibliográficos
Autores principales: Chiang, Shian-Huey, Harrington, W. Wallace, Luo, Guizhen, Milliken, Naphtali O., Ulrich, John C., Chen, Jing, Rajpal, Deepak K., Qian, Ying, Carpenter, Tiffany, Murray, Rusty, Geske, Robert S., Stimpson, Stephen A., Kramer, Henning F., Haffner, Curt D., Becherer, J. David, Preugschat, Frank, Billin, Andrew N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546114/
https://www.ncbi.nlm.nih.gov/pubmed/26287487
http://dx.doi.org/10.1371/journal.pone.0134927

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