GRAF1 deficiency blunts sarcolemmal injury repair and exacerbates cardiac and skeletal muscle pathology in dystrophin-deficient mice

BACKGROUND: The plasma membranes of striated muscle cells are particularly susceptible to rupture as they endure significant mechanical stress and strain during muscle contraction, and studies have shown that defects in membrane repair can contribute to the progression of muscular dystrophy. The syn...

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Detalles Bibliográficos
Autores principales: Lenhart, Kaitlin C., O’Neill, Thomas J., Cheng, Zhaokang, Dee, Rachel, Demonbreun, Alexis R., Li, Jianbin, Xiao, Xiao, McNally, Elizabeth M., Mack, Christopher P., Taylor, Joan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546166/
https://www.ncbi.nlm.nih.gov/pubmed/26301073
http://dx.doi.org/10.1186/s13395-015-0054-6

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