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Inactivation of tumor suppressor gene pten in early and advanced gallbladder cancer

BACKGROUND: PTEN is a tumor suppressor gene that regulates the PTEN/PI3k/AKT/mTOR pathway, which is frequently altered in human cancers including gallbladder cancer (GBC). To determine the frequency of PTEN expression in GBC and to establish its relation to clinical and morphological parameters and...

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Detalles Bibliográficos
Autores principales:	Roa, Iván, de Toro, Gonzalo, Fernández, Fernanda, Game, Anakaren, Muñoz, Sergio, de Aretxabala, Xabier, Javle, Milind
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546176/ https://www.ncbi.nlm.nih.gov/pubmed/26294099 http://dx.doi.org/10.1186/s13000-015-0381-2

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