Global analysis of DNA methylation in hepatocellular carcinoma by a liquid hybridization capture-based bisulfite sequencing approach

BACKGROUND: Epigenetic alterations, such as aberrant DNA methylation of promoter and enhancer regions, which lead to atypical gene expression, have been associated with carcinogenesis. In hepatocellular carcinoma (HCC), genome-wide analysis of methylation has only recently been used. For a better un...

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Detalles Bibliográficos
Autores principales: Gao, Fei, Liang, Huifang, Lu, Hanlin, Wang, Junwen, Xia, Meng, Yuan, Zhimei, Yao, Yu, Wang, Tong, Tan, Xiaolong, Laurence, Arian, Xu, Hua, Yu, Jingjing, Xiao, Wei, Chen, Wei, Zhou, Ming, Zhang, Xiuqing, Chen, Qian, Chen, Xiaoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546208/
https://www.ncbi.nlm.nih.gov/pubmed/26300991
http://dx.doi.org/10.1186/s13148-015-0121-1

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