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Discovery of Novel Plasmodium falciparum Pre-Erythrocytic Antigens for Vaccine Development

BACKGROUND: Nearly 100% protection against malaria infection can be achieved in humans by immunization with P. falciparum radiation-attenuated sporozoites (RAS). Although it is thought that protection is mediated by T cell and antibody responses, only a few of the many pre-erythrocytic (sporozoite a...

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Detalles Bibliográficos
Autores principales: Aguiar, Joao C., Bolton, Jessica, Wanga, Joyce, Sacci, John B., Iriko, Hideyuki, Mazeika, Julie K., Han, Eun-Taek, Limbach, Keith, Patterson, Noelle B., Sedegah, Martha, Cruz, Ann-Marie, Tsuboi, Takafumi, Hoffman, Stephen L., Carucci, Daniel, Hollingdale, Michael R., Villasante, Eileen D., Richie, Thomas L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546230/
https://www.ncbi.nlm.nih.gov/pubmed/26292257
http://dx.doi.org/10.1371/journal.pone.0136109