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let-7b suppresses apoptosis and autophagy of human mesenchymal stem cells transplanted into ischemia/reperfusion injured heart 7by targeting caspase-3

INTRODUCTION: Mesenchymal stem cells (MSCs) have therapeutic potential for the repair of myocardial injury. The efficacy of MSC therapy for myocardial regeneration mainly depends on the survival of cells after transplantation into the infarcted heart. In the transplanted regions, reactive oxygen spe...

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Detalles Bibliográficos
Autores principales: Ham, Onju, Lee, Se-Yeon, Lee, Chang Youn, Park, Jun-Hee, Lee, Jiyun, Seo, Hyang-Hee, Cha, Min-Ji, Choi, Eunhyun, Kim, Soonhag, Hwang, Ki-Chul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546263/
https://www.ncbi.nlm.nih.gov/pubmed/26296645
http://dx.doi.org/10.1186/s13287-015-0134-x