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HIV-1 protease cleaves the serine-threonine kinases RIPK1 and RIPK2
BACKGROUND: HIV-1 protease (PR) is essential for viral infectivity as it cleaves Gag and Gag-Pol polyprotein precursors during viral maturation. Recent evidence suggests that cellular proteins can also be cleaved by PR, perhaps representing an important viral strategy to counter host defense mechani...
Autores principales: | Wagner, Roland N., Reed, John C., Chanda, Sumit K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546280/ https://www.ncbi.nlm.nih.gov/pubmed/26297639 http://dx.doi.org/10.1186/s12977-015-0200-6 |
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