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Sex Differences in Dose Escalation and Overdose Death during Chronic Opioid Therapy: A Population-Based Cohort Study
BACKGROUND: The use of opioids for noncancer pain is widespread, and more than 16,000 die of opioid-related causes in the United States annually. The patients at greatest risk of death are those receiving high doses of opioids. Whether sex influences the risk of dose escalation or opioid-related mor...
Autores principales: | Kaplovitch, Eric, Gomes, Tara, Camacho, Ximena, Dhalla, Irfan A., Mamdani, Muhammad M., Juurlink, David N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546305/ https://www.ncbi.nlm.nih.gov/pubmed/26291716 http://dx.doi.org/10.1371/journal.pone.0134550 |
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