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Short-term high glucose exposure impairs insulin signaling in endothelial cells

BACKGROUND: Hyperglycemia is the hallmark of diabetes and its cardiovascular complications. Insulin plays an important role in the regulation of vascular homeostasis and maintenance of endothelial function. Insulin signaling occurs after binding to the insulin receptor, causing activation of two sep...

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Detalles Bibliográficos
Autores principales:	De Nigris, Valeria, Pujadas, Gemma, La Sala, Lucia, Testa, Roberto, Genovese, Stefano, Ceriello, Antonio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Original Investigation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546318/ https://www.ncbi.nlm.nih.gov/pubmed/26297582 http://dx.doi.org/10.1186/s12933-015-0278-0

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