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Reduction in peripheral vascular resistance predicts improvement in insulin clearance following weight loss
BACKGROUND: The hyperinsulinemia of obesity is a function of both increased pancreatic insulin secretion and decreased insulin clearance, and contributes to cardiovascular risk. Whilst weight loss is known to enhance insulin clearance, there is a paucity of data concerning the underlying mechanisms....
Autores principales: | Straznicky, Nora E., Grima, Mariee T., Sari, Carolina I., Lambert, Elisabeth A., Phillips, Sarah E., Eikelis, Nina, Kobayashi, Daisuke, Hering, Dagmara, Mariani, Justin A., Dixon, John B., Nestel, Paul J., Karapanagiotidis, Sofie, Schlaich, Markus P., Lambert, Gavin W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546319/ https://www.ncbi.nlm.nih.gov/pubmed/26297500 http://dx.doi.org/10.1186/s12933-015-0276-2 |
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