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Intermittent high dose proton pump inhibitor enhances the antitumor effects of chemotherapy in metastatic breast cancer

BACKGROUND: Acidity is a hallmark of malignant tumor, representing a very efficient mechanism of chemoresistance. Proton pump inhibitors (PPI) at high dosage have been shown to sensitize chemoresistant human tumor cells and tumors to cytotoxic molecules. The aim of this pilot study was to investigat...

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Detalles Bibliográficos
Autores principales:	Wang, Bi-Yun, Zhang, Jian, Wang, Jia-Lei, Sun, Si, Wang, Zhong-Hua, Wang, Lei-Ping, Zhang, Qun-Ling, Lv, Fang-Fang, Cao, En-Ying, Shao, Zhi-Min, Fais, Stefano, Hu, Xi-Chun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546346/ https://www.ncbi.nlm.nih.gov/pubmed/26297142 http://dx.doi.org/10.1186/s13046-015-0194-x

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