Cargando…

Which Way In? The RalF Arf-GEF Orchestrates Rickettsia Host Cell Invasion

Bacterial Sec7-domain-containing proteins (RalF) are known only from species of Legionella and Rickettsia, which have facultative and obligate intracellular lifestyles, respectively. L. pneumophila RalF, a type IV secretion system (T4SS) effector, is a guanine nucleotide exchange factor (GEF) of ADP...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rennoll-Bankert, Kristen E., Rahman, M. Sayeedur, Gillespie, Joseph J., Guillotte, Mark L., Kaur, Simran J., Lehman, Stephanie S., Beier-Sexton, Magda, Azad, Abdu F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546372/ https://www.ncbi.nlm.nih.gov/pubmed/26291822 http://dx.doi.org/10.1371/journal.ppat.1005115

Ejemplares similares

RalF-Mediated Activation of Arf6 Controls Rickettsia typhi Invasion by Co-Opting Phosphoinositol Metabolism
por: Rennoll-Bankert, Kristen E., et al.
Publicado: (2016)

The Cat Flea (Ctenocephalides felis) Immune Deficiency Signaling Pathway Regulates Rickettsia typhi Infection
por: Rennoll, Sherri A., et al.
Publicado: (2017)

Wholly Rickettsia! Reconstructed Metabolic Profile of the Quintessential Bacterial Parasite of Eukaryotic Cells
por: Driscoll, Timothy P., et al.
Publicado: (2017)

A Novel Membrane Sensor Controls the Localization and ArfGEF Activity of Bacterial RalF
por: Folly-Klan, Marcia, et al.
Publicado: (2013)

Risk1, a Phosphatidylinositol 3-Kinase Effector, Promotes Rickettsia typhi Intracellular Survival
por: Voss, Oliver H., et al.
Publicado: (2020)

Rickettsia typhi Possesses Phospholipase A(2) Enzymes that Are Involved in Infection of Host Cells
por: Rahman, M. Sayeedur, et al.
Publicado: (2013)

The Capping Domain in RalF Regulates Effector Functions
por: Alix, Eric, et al.
Publicado: (2012)

Plasmids and Rickettsial Evolution: Insight from Rickettsia felis
por: Gillespie, Joseph J., et al.
Publicado: (2007)

Rickettsia Lipid A Biosynthesis Utilizes the Late Acyltransferase LpxJ for Secondary Fatty Acid Addition
por: Guillotte, Mark L., et al.
Publicado: (2018)

Lipid A Structural Divergence in Rickettsia Pathogens
por: Guillotte, Mark L., et al.
Publicado: (2021)

Revealing the activation mechanism of autoinhibited RalF by integrated simulation and experimental approaches
por: Dudas, Balint, et al.
Publicado: (2021)

A chromosome-level assembly of the cat flea genome uncovers rampant gene duplication and genome size plasticity
por: Driscoll, Timothy P., et al.
Publicado: (2020)

An Anomalous Type IV Secretion System in Rickettsia Is Evolutionarily Conserved
por: Gillespie, Joseph J., et al.
Publicado: (2009)

Ral-Arf6 crosstalk regulates Ral dependent exocyst trafficking and anchorage independent growth signalling
por: Pawar, Archana, et al.
Publicado: (2016)

Genome-wide screen for temperature-regulated genes of the obligate intracellular bacterium, Rickettsia typhi
por: Dreher-Lesnick, Sheila M, et al.
Publicado: (2008)

ARF GTPases and their GEFs and GAPs: concepts and challenges
por: Sztul, Elizabeth, et al.
Publicado: (2019)

Surface Proteome Analysis and Characterization of Surface Cell Antigen (Sca) or Autotransporter Family of Rickettsia typhi
por: Sears, Khandra T., et al.
Publicado: (2012)

Structural Insight into How Bacteria Prevent Interference between Multiple Divergent Type IV Secretion Systems
por: Gillespie, Joseph J., et al.
Publicado: (2015)

Regulation of a Golgi Flippase by Phosphoinositides and an ArfGEF
por: Natarajan, Paramasivam, et al.
Publicado: (2009)

Developmental fidelity is imposed by genetically separable RalGEF activities that mediate opposing signals
por: Shin, Hanna, et al.
Publicado: (2019)

RalB regulates contractility-driven cancer dissemination upon TGFβ stimulation via the RhoGEF GEF-H1
por: Biondini, Marco, et al.
Publicado: (2015)

The Arf-GEF GBF1 undergoes multi-domain structural shifts to activate Arf at the Golgi
por: Meissner, Justyna M., et al.
Publicado: (2023)

Insulated Switches: Dual-Function Protein RalGEF(RGL-1) Promotes Developmental Fidelity
por: Duong, Tam, et al.
Publicado: (2020)

Geographic Association of Rickettsia felis-Infected Opossums with Human Murine Typhus, Texas
por: Boostrom, Ardys, et al.
Publicado: (2002)

The human Rgr oncogene is overexpressed in T cell malignancies and induces transformation by acting as a GEF for Ras and Ral
por: Osei-Sarfo, Kwame, et al.
Publicado: (2011)

Autoregulation of Sec7 Arf-GEF activity and localization by positive feedback
por: Richardson, Brian C., et al.
Publicado: (2012)

PH Domain-Arf G Protein Interactions Localize the Arf-GEF Steppke for Cleavage Furrow Regulation in Drosophila
por: Lee, Donghoon M., et al.
Publicado: (2015)

Louse- and flea-borne rickettsioses: biological and genomic analyses
por: Gillespie, Joseph J., et al.
Publicado: (2009)

Pathogenic, but Not Nonpathogenic, Rickettsia spp. Evade Inflammasome-Dependent IL-1 Responses To Establish an Intracytosolic Replication Niche
por: Voss, Oliver H., et al.
Publicado: (2022)

MAZ promotes prostate cancer bone metastasis through transcriptionally activating the KRas-dependent RalGEFs pathway
por: Yang, Qing, et al.
Publicado: (2019)

Wolfgang Pauli with Ralf Kronig
por: Unknown
Publicado: (1955)

Wolfgang Pauli with Ralf Kronig
por: Unknown
Publicado: (1955)

Integrated Conformational and Lipid-Sensing Regulation of Endosomal ArfGEF BRAG2
por: Aizel, Kaheina, et al.
Publicado: (2013)

NtGNL1a ARF-GEF acts in endocytosis in tobacco cells
por: Jelínková, Adriana, et al.
Publicado: (2015)

Rickettsia-host interaction: strategies of intracytosolic host colonization
por: Voss, Oliver H, et al.
Publicado: (2021)

A single class of ARF GTPase activated by several pathway-specific ARF-GEFs regulates essential membrane traffic in Arabidopsis
por: Singh, Manoj K., et al.
Publicado: (2018)

Disrupting Protein Expression with Peptide Nucleic Acids Reduces Infection by Obligate Intracellular Rickettsia
por: Pelc, Rebecca S., et al.
Publicado: (2015)

Lessons from Anaplasma phagocytophilum: Chromatin Remodeling by Bacterial Effectors
por: Rennoll-Bankert, Kristen E, et al.
Publicado: (2012)

Arf6 recruits the Rac GEF Kalirin to the plasma membrane facilitating Rac activation
por: Koo, Tae Hyeon, et al.
Publicado: (2007)

Ancient complement and lineage-specific evolution of the Sec7 ARF GEF proteins in eukaryotes
por: Pipaliya, Shweta V., et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_p4kb936ljbmhgmg9rlnm1taofh