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Genetic Analysis and Species Specific Amplification of the Artemisinin Resistance-Associated Kelch Propeller Domain in P. falciparum and P. vivax

Plasmodium falciparum resistance to artemisinin has emerged in the Greater Mekong Subregion and now poses a threat to malaria control and prevention. Recent work has identified mutations in the kelch propeller domain of the P. falciparum K13 gene to be associated artemisinin resistance as defined by...

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Detalles Bibliográficos
Autores principales: Talundzic, Eldin, Chenet, Stella M., Goldman, Ira F., Patel, Dhruviben S., Nelson, Julia A., Plucinski, Mateusz M., Barnwell, John W., Udhayakumar, Venkatachalam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546394/
https://www.ncbi.nlm.nih.gov/pubmed/26292024
http://dx.doi.org/10.1371/journal.pone.0136099