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Genetic Analysis and Species Specific Amplification of the Artemisinin Resistance-Associated Kelch Propeller Domain in P. falciparum and P. vivax
Plasmodium falciparum resistance to artemisinin has emerged in the Greater Mekong Subregion and now poses a threat to malaria control and prevention. Recent work has identified mutations in the kelch propeller domain of the P. falciparum K13 gene to be associated artemisinin resistance as defined by...
Autores principales: | Talundzic, Eldin, Chenet, Stella M., Goldman, Ira F., Patel, Dhruviben S., Nelson, Julia A., Plucinski, Mateusz M., Barnwell, John W., Udhayakumar, Venkatachalam |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546394/ https://www.ncbi.nlm.nih.gov/pubmed/26292024 http://dx.doi.org/10.1371/journal.pone.0136099 |
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