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The Wnt Frizzled Receptor MOM-5 Regulates the UNC-5 Netrin Receptor through Small GTPase-Dependent Signaling to Determine the Polarity of Migrating Cells
Wnt and Netrin signaling regulate diverse essential functions. Using a genetic approach combined with temporal gene expression analysis, we found a regulatory link between the Wnt receptor MOM-5/Frizzled and the UNC-6/Netrin receptor UNC-5. These two receptors play key roles in guiding cell and axon...
Autores principales: | Levy-Strumpf, Naomi, Krizus, Meghan, Zheng, Hong, Brown, Louise, Culotti, Joseph G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546399/ https://www.ncbi.nlm.nih.gov/pubmed/26292279 http://dx.doi.org/10.1371/journal.pgen.1005446 |
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