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The Wnt Frizzled Receptor MOM-5 Regulates the UNC-5 Netrin Receptor through Small GTPase-Dependent Signaling to Determine the Polarity of Migrating Cells

Wnt and Netrin signaling regulate diverse essential functions. Using a genetic approach combined with temporal gene expression analysis, we found a regulatory link between the Wnt receptor MOM-5/Frizzled and the UNC-6/Netrin receptor UNC-5. These two receptors play key roles in guiding cell and axon...

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Detalles Bibliográficos
Autores principales: Levy-Strumpf, Naomi, Krizus, Meghan, Zheng, Hong, Brown, Louise, Culotti, Joseph G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546399/
https://www.ncbi.nlm.nih.gov/pubmed/26292279
http://dx.doi.org/10.1371/journal.pgen.1005446

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