Carnosol Inhibits Pro-Inflammatory and Catabolic Mediators of Cartilage Breakdown in Human Osteoarthritic Chondrocytes and Mediates Cross-Talk between Subchondral Bone Osteoblasts and Chondrocytes

AIM: The aim of this work was to evaluate the effects of carnosol, a rosemary polyphenol, on pro-inflammatory and catabolic mediators of cartilage breakdown in chondrocytes and via bone-cartilage crosstalk. MATERIALS AND METHODS: Osteoarthritic (OA) human chondrocytes were cultured in alginate beads...

Descripción completa

Detalles Bibliográficos
Autores principales: Sanchez, Christelle, Horcajada, Marie-Noëlle, Membrez Scalfo, Fanny, Ameye, Laurent, Offord, Elizabeth, Henrotin, Yves
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546401/
https://www.ncbi.nlm.nih.gov/pubmed/26292290
http://dx.doi.org/10.1371/journal.pone.0136118

Ejemplares similares

Ejemplares similares