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Rhoptry Proteins ROP5 and ROP18 Are Major Murine Virulence Factors in Genetically Divergent South American Strains of Toxoplasma gondii
Toxoplasma gondii has evolved a number of strategies to evade immune responses in its many hosts. Previous genetic mapping of crosses between clonal type 1, 2, and 3 strains of T. gondii, which are prevalent in Europe and North America, identified two rhoptry proteins, ROP5 and ROP18, that function...
Autores principales: | Behnke, Michael S., Khan, Asis, Lauron, Elvin J., Jimah, John R., Wang, Qiuling, Tolia, Niraj H., Sibley, L. David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546408/ https://www.ncbi.nlm.nih.gov/pubmed/26291965 http://dx.doi.org/10.1371/journal.pgen.1005434 |
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