Biophysical Characterization of a Vaccine Candidate against HIV-1: The Transmembrane and Membrane Proximal Domains of HIV-1 gp41 as a Maltose Binding Protein Fusion

The membrane proximal region (MPR, residues 649–683) and transmembrane domain (TMD, residues 684–705) of the gp41 subunit of HIV-1’s envelope protein are highly conserved and are important in viral mucosal transmission, virus attachment and membrane fusion with target cells. Several structures of th...

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Detalles Bibliográficos
Autores principales: Gong, Zhen, Martin-Garcia, Jose M., Daskalova, Sasha M., Craciunescu, Felicia M., Song, Lusheng, Dörner, Katerina, Hansen, Debra T., Yang, Jay-How, LaBaer, Joshua, Hogue, Brenda G., Mor, Tsafrir S., Fromme, Petra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546420/
https://www.ncbi.nlm.nih.gov/pubmed/26295457
http://dx.doi.org/10.1371/journal.pone.0136507

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