Kras activation in p53-deficient myoblasts results in high-grade sarcoma formation with impaired myogenic differentiation

While genomic studies have improved our ability to classify sarcomas, the molecular mechanisms involved in the formation and progression of many sarcoma subtypes are unknown. To better understand developmental origins and genetic drivers involved in rhabdomyosarcomagenesis, we describe a novel sarco...

Descripción completa

Detalles Bibliográficos
Autores principales: McKinnon, Timothy, Venier, Rosemarie, Dickson, Brendan C., Kabaroff, Leah, Alkema, Manon, Chen, Li, Shern, Jack F., Yohe, Marielle E., Khan, Javed, Gladdy, Rebecca A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546462/
https://www.ncbi.nlm.nih.gov/pubmed/25992772

Ejemplares similares

Ejemplares similares