Anticancer activity of halofuginone in a preclinical model of osteosarcoma: inhibition of tumor growth and lung metastases

Osteosarcoma is the main malignant primary bone tumor in children and adolescents for whom the prognosis remains poor, especially when metastases are present at diagnosis. Because we recently demonstrated that TGF-β/Smad cascade plays a crucial role in osteosarcoma metastatic progression, we investi...

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Detalles Bibliográficos
Autores principales: Lamora, Audrey, Mullard, Mathilde, Amiaud, Jérôme, Brion, Régis, Heymann, Dominique, Redini, Françoise, Verrecchia, Franck
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546476/
https://www.ncbi.nlm.nih.gov/pubmed/26015407

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